Open AccessThe Potency of Hibiscus rosa-sinensis Linn. Leaves Ethanol Extract as Hair Growth
Author(s) -
Imam Budi Putra,
Nelva Karmila Jusuf,
Imam Bagus Sumantri
Publication year - 2020
Publication title -
open access macedonian journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.288
H-Index - 17
ISSN - 1857-9655
DOI - 10.3889/oamjms.2020.4211
Subject(s) - hibiscus , tannin , phytochemical , flavonoid , traditional medicine , saponin , ethanol , potency , glycoside , botany , medicine , in vivo , food science , chemistry , biology , biochemistry , in vitro , antioxidant , alternative medicine , microbiology and biotechnology , pathology
Hair is one of the organs and crowns for all people. Hair loss will really bother for most people. One of the plants that can be used as hair growth is Hibiscus rosa-sinensis Linn.
OBJECTIVE: The objective of the study was to find the potency of H. rosa-sinensis leaves ethanol extracts as hair growth.
METHODS: In this research, simplicia and extracts were made from hibiscus leaves using ethanol as a solvent. Simplicia and extracts were tested for phytochemical screening and characterization of each. The extract obtained was tested in vivo with animals test by observing mouse’s hair growth for 25 days of observation.
RESULTS: Simplicia and ethanol extract of Hibiscus leaves contain flavonoids, alkaloids, glycosides, tannins, and steroids/terpenoids. The characteristics of Hibiscus leaves simplicia and extract had water content (9.71% vs. 10.65%), water-soluble extract content (19.91% vs. 27.58%), ethanol-soluble extract content (37.86% vs. 49.51%), total ash content (7.96% vs. 9.46%), and acid-insoluble ash content (0.78% vs. 1.28%). In vivo testing with animals, ethanol extract of Hibiscus leaves had an effect as a hair growth until the 25th day with an average concentration of 2.5% (14 mm), 5% (16 mm), and 10% (19 mm).
DISCUSSION: The extract of Hibiscus leaves that showed the presence of carbohydrate, alkaloid, flavonoid, steroids, protein, tannin, and amino acids. The presence of active constituents such as flavonoids and tannins may be responsible for hair growth activity.
CONCLUSION: The ethanol extracts of H. rosa-sinensis leaves can increase hair growth, at optimum concentrations of 10% extract.