Open AccessAssessment of index value performance of enzyme immunoassay test in predicting the diagnosis of human brucellosis
Author(s) -
Ayfer Bakır,
Mustafa Mustafa,
Sema Alaçam,
Ali Korhan Sığ,
Nurten Bekiroglu,
Mehmet Tevfik Yavuz
Publication year - 2022
Publication title -
journal of infection in developing countries
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.322
H-Index - 49
eISSN - 2036-6590
pISSN - 1972-2680
DOI - 10.3855/jidc.15347
Subject(s) - brucellosis , brucella , direct agglutination test , medicine , immunoglobulin m , antibody , immunology , serology , immunoassay , latex fixation test , predictive value , gastroenterology , immunoglobulin g
Clinical presentation of brucellosis is variable. Therefore, it must be confirmed with laboratory findings. Standard tube agglutination test (STAT) is commonly used for diagnosis of brucellosis. ELISA tests differentiate between IgM and IgG antibodies. However, there are evidences revealing that they do not have sufficient specificity. This study aimed to determine an ELISA optimal index value in the diagnosis of brucellosis.