Open AccessThe Effect of Veno-Arterial Extracorporeal Oxygenation and Nasogastric Tube Administration on the Pharmacokinetic Profile of Abacavir, Lamivudine and Dolutegravir: A Case Report
Author(s) -
Alison L Blackman,
Emily Heil,
Aaron S. Devanathan,
Neha Sheth Pandit
Publication year - 2019
Publication title -
antiviral therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 87
eISSN - 2040-2058
pISSN - 1359-6535
DOI - 10.3851/imp3355
Subject(s) - medicine , dolutegravir , abacavir , extracorporeal membrane oxygenation , pharmacokinetics , lamivudine , population , gastroenterology , human immunodeficiency virus (hiv) , anesthesia , viral load , antiretroviral therapy , virology , virus , hepatitis b virus , environmental health
Pharmacokinetic (PK) changes can affect antiretroviral (ARV) systemic exposure for critically ill patients living with HIV (CI-PLWH). Studies to guide ARV adjustments in this population are limited.