Open AccessAre Circulating miRNAs Predictive of Response to Therapy?
Author(s) -
Lava K. Kannappa
Publication year - 2019
Publication title -
the physician
Language(s) - English
Resource type - Journals
eISSN - 2732-5148
pISSN - 2732-513X
DOI - 10.38192/1.6.1.c11
Subject(s) - microrna , colorectal cancer , medicine , oncology , cancer , bioinformatics , biology , gene , genetics
Colorectal cancer (CRC) is the third commonest cancer with nearly 1.4 million new cases identified throughout the world in 2012. There is a pressing need for a new non-invasive blood-based test to improve early detection and monitoring of CRC. MiRNAs are small non-coding RNAs involved in fundamental cell processes such as proliferation, survival and death. Studies have identified miRNAs in plasma of cancer patients in a stable form. This study aimed to evaluate whether circulating microRNAs are predictive of response to therapy.