Are Circulating miRNAs Predictive of Response to Therapy? | Zendy

Lava Krishna Kanappa | Zendy

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Are Circulating miRNAs Predictive of Response to Therapy?

Author(s) -

Lava Krishna Kanappa

Publication year - 2019

Publication title -

the physician

Language(s) - English

Resource type - Journals

eISSN - 2732-5148

pISSN - 2732-513X

DOI - 10.38192/1.6.1.c11

Subject(s) - microrna , colorectal cancer , medicine , oncology , cancer , bioinformatics , biology , gene , genetics

Colorectal cancer (CRC) is the third commonest cancer with nearly 1.4 million new cases identified throughout the world in 2012. There is a pressing need for a new non-invasive blood-based test to improve early detection and monitoring of CRC. MiRNAs are small non-coding RNAs involved in fundamental cell processes such as proliferation, survival and death. Studies have identified miRNAs in plasma of cancer patients in a stable form. This study aimed to evaluate whether circulating microRNAs are predictive of response to therapy.

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