Open AccessChallenging One Model With Many Stimuli: Simulating Responses in the Inferior Colliculus
Author(s) -
Langchen Fan,
Kenneth S. Henry,
Laurel H. Carney
Publication year - 2018
Publication title -
acta acustica united with acustica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.283
H-Index - 57
eISSN - 1610-1928
pISSN - 1861-9959
DOI - 10.3813/aaa.919249
Subject(s) - inferior colliculus , stimulus (psychology) , neuroscience , receptive field , psychophysics , superior colliculus , psychology , computer science , perception , cognitive psychology , nucleus
Existing models to explain human psychophysics or neural responses are typically designed for a specific stimulus type and often fail for other stimuli. The ultimate goal for a neural model is to simulate responses to many stimuli, which may provide better insights into neural mechanisms. We tested the ability of modified same-frequency inhibition-excitation models for inferior colliculus neurons to simulate individual neuron responses to both amplitude-modulated sounds and tone-in-noise stimuli. Modifications to the model were guided by receptive fields computed with 2nd-order Wiener kernel analysis. This approach successfully simulated many individual neurons' responses to different types of stimuli. Other neurons suggest limitations and future directions for modeling efforts.