Open AccessPREVALENCE AND STRUCTURE OF CEREBROVASCULAR COMPLICATIONS OF ARTERIAL HYPERTENSION IN UZBEK PATIENTS WITH VARIOUS ANGIOTENSIN-CONVERTING ENZYME AND APOLIPOPROTEINE E. GENE POLYMORPHISMS
Author(s) -
N. U. Makhkamova,
A. I. Khodjayev
Publication year - 2012
Publication title -
evrazijskij kardiologičeskij žurnal
Language(s) - English
Resource type - Journals
eISSN - 2305-0748
pISSN - 2225-1685
DOI - 10.38109/2225-1685-2012-2-55-58
Subject(s) - polymorphism (computer science) , apolipoprotein e , angiotensin converting enzyme , medicine , gene , cardiology , blood pressure , genetics , biology , genotype , disease
The purpose of the given work was frequency and structure studing cerebrovaskular complications at sick suffering hypertensive illness and revailing of their interrelation with polymorphism of genes ACE and APOE. Patients of both sexes at the age of 25-75 years suffering arterial hypertension (AH) 1 and 3 stages are for this purpose surveyed. Clinic-neurologic, biochemical and molekular-genetic research for definition of polymorphisms of genes ACE and APOE is for this purpose conducted. Are revealed to associate some polymorphisms of the studied genes with the heaviest complications AH.