Ảnh hưởng của tình trạng dinh dưỡng lên chất lượng sống của bệnh nhân ung thư được điều trị hóa chất tại khoa Ung bướu Bệnh viện trường Đại học Y Dược Huế

ASSESSING THE RELATIONSHIP OF NUTRITIONAL STATUS TO THE QUALITY OF LIFE OF CANCER PATIENTS RECEIVING CHEMOTHERAPY AT THE ONCOLOGY DEPARTMENT OF HUE COLLEGE OF MEDICINE AND PHARMACYBackground: Cancer is the second leading cause of death globally as well as in Vietnam. Chemotherapy is a systemic treatment with chemical drugs. Chemotherapy often causes many problems related to physical, mental and toxicity, which have an effect on the quality of life and nutritional status of patients. While malnutrition has been shown to be common in cancer patients, its impacts on the patient's quality of life have not been adequately studied, especially in Vietnam.Objective: To evaluate the quality of life of cancer patients receiving chemotherapy. To determine the relationship of nutritional status to the quality of life in these patients.Methods: A cross-sectional study was conducted on 82 patients with cancer during a chemotherapytreatment at the Department of Oncology, Hue College of Medicine and Pharmacy from February 2018 to February 2019. Assessing the quality of life by the Quality of Life Questionnaire of the European Organizationfor Research and Treatment of Cancer (EORTC QLQ-C30). Descriptive statistics and test Chi-square and Fisher exact were performed to analyze the quality of life parameters and the relationship between nutritional status and quality of life.Results: A total of 82 subjects were included in this study, 51 subjects (62.20%) were males and 31 subjects (37.80%) were females, the mean age was 58.98 ± 12.52. The most common type of cancer is gastrointestinal cancer (37.80%), the highest stage of cancer is stage 4 (56.10%), symptomatic chemotherapy accounts for the highest rate with 53.70% and the average number of chemotherapy cycles is 4.00 ± 3.68. The study shows that the meanglobal health status is 50.00 ± 16.89, the best quality of life score is in the field of cognitive function with 83.33 points, the worst quality of life score is in the symptoms field of insomnia and in the financial difficulties with 66.67 points. Results from Chi-square and Fisher Exact analysis test revealed a statistically significant association between the risk of malnutrition according to SGA classification and the role functioning offunctional scales (p <0.05).Conclusions: The quality of life of cancer patients is generally good. The nutritional status affects the quality of life in the field of role function.Keywords: Quality of life, cancer, chemotherapy.