Open AccessDiagnostic Accuracy of Mammographic and Sonographic Findings in the Differentiation of Palpable Breast Masses taking Histopathology as a Gold Standard
Author(s) -
Sadaf Ayesha,
Raham Bacha,
Tayyaba Akhter,
Mehreen Fatima,
Syed Amir Gilani,
Syed Yousaf Farooq,
Muhammad Abrar Yousaf,
Muhammad Uzair,
Mahjabeen Liaqat,
Maimoona Rasool
Publication year - 2021
Publication title -
journal of pharmacy and pharmaceutical sciences
Language(s) - English
Resource type - Journals
ISSN - 2311-4673
DOI - 10.37962/jpps.v9i1.500
Subject(s) - histopathology , medicine , mammography , gold standard (test) , breast lumps , breast cancer , radiology , ultrasound , breast ultrasound , diagnostic accuracy , cancer , pathology
Background: The Presence of palpable breast mass may be an indication of breast cancer. Early and accurate diagnosis for the breast masses is important for therapeutic purpose.
Purpose: To assess the diagnostic accuracy of mammographic and sonographic findings in the differentiation of palpable breast masses taking histopathology as a gold standard.
Materials and Methods: 134 females were involved in the study. Sonographic and mammographic findings of palpable breast masses were obtained with the help of which diagnostic accuracy of ultrasound and mammography was calculated while taking histopathology as a gold standard.
Results: Mean age in 134 females was found to be 44.2±4.7 years. Sn, Sp, PPV, NPV, disease prevalence and accuracy of ultrasound in diagnosis of palpable breast lumps were 99.09%, 79.17%, 95.61%, 95.00%, 82.09% and 95.52% respectively. Sn, Sp, PPV, NPV and accuracy of mammography in diagnosis of palpable breast lumps were 95.45%, 62.50%, 92.11%, 75.00% and 89.55% while disease prevalence was same as that of ultrasound i.e. 82.09% respectively.
Conclusion: Ultrasound showed higher diagnostic accuracy in the evaluation of palpable breast masses than mammography while taking histopathology as a gold standard. It is noteworthy in differentiating breast masses.