Open AccessUPDATE OF CARDIOVASCULAR AUTONOMIC NEUROPATHY IN PATIENTS WITH DIABETES
Author(s) -
Andra-Eleica,
Carmen Dobjansch,
Oana Parliteanu,
Emilia Rusu,
Gabriela Radulian
Publication year - 2021
Publication title -
romanian medical journal
Language(s) - English
Resource type - Journals
eISSN - 2069-606X
pISSN - 1220-5478
DOI - 10.37897/rmj.2021.2.6
Subject(s) - medicine , orthostatic vital signs , diabetes mellitus , autonomic neuropathy , cardiology , heart rate variability , reflex , tachycardia , heart rate , intensive care medicine , blood pressure , endocrinology , biology , cell culture , genetics , neuroblastoma
The burden of diabetic cardiovascular autonomic neuropathy (CAN) is expected to increase due to the diabetes epidemic and its early and widespread appearance. CAN has a definite prognostic role for mortality and cardiovascular morbidity. Putative mechanisms for this are tachycardia, QT interval prolongation, orthostatic hypotension, reverse dipping, and impaired heart rate variability, while emerging mechanisms like inflammation support the pervasiveness of autonomic dysfunction. Efforts to overcome CAN under-diagnosis are: by promoting screening for symptoms and signs; by simplifying cardiovascular reflex tests.