Open AccessThe spectrum of clinical manifestations of antiphospholipid syndrome
Author(s) -
Camelia Cristina Diaconu,
G. Dediu,
Bianca Paraschiv
Publication year - 2015
Publication title -
romanian medical journal
Language(s) - English
Resource type - Journals
eISSN - 2069-606X
pISSN - 1220-5478
DOI - 10.37897/rmj.2015.1.11
Subject(s) - medicine , antiphospholipid syndrome , thrombosis , venous thrombosis , disease , autoimmune disease , pregnancy , broad spectrum , chemistry , biology , combinatorial chemistry , genetics
Antiphospholipid syndrome is an acquired autoimmune disease characterized by the appearance of thrombosis (venous, arterial and microvascular) and/or complications during pregnancy, in the presence of antiphospholipid antibodies. The clinical spectrum of the disease is now more complex and include organ-specific and systemic symptoms induced not only by thrombotic mechanisms, but also immune-mediated. Patients diagnosed with antiphospholipid syndrome should be evaluated clinically and laboratory periodically to detect lung damage, cardiac, neurological, skin, eye, hematological, gastrointestinal complications.