COULD ANTI-SYNTHETASE SYNDROME BE A GOOD PREDICTOR FACTOR FOR INTERSTITIAL LUNG DISEASE? | Zendy

Sineta Cristina Firulescu | Zendy; Paulina Lucia Ciurea | Zendy; Cristina Dorina Pârvănescu | Zendy; Beatrice Andreea Chisălau | Zendy; Andreea Lili Bărbulescu | Zendy; Cristina Criveanu | Zendy; Adina Turcu-Știolică | Zendy; Roxana Edmee Mustafa | Zendy; Florentin Ananu Vreju | Zendy

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COULD ANTI-SYNTHETASE SYNDROME BE A GOOD PREDICTOR FACTOR FOR INTERSTITIAL LUNG DISEASE?

Author(s) -

Sineta Cristina Firulescu,

Paulina Lucia Ciurea,

Cristina Dorina Pârvănescu,

Beatrice Andreea Chisălau,

Andreea Lili Bărbulescu,

Cristina Criveanu,

Adina Turcu-Știolică,

Roxana Edmee Mustafa,

Florentin Ananu Vreju

Publication year - 2017

Publication title -

romanian journal of rheumatology

Language(s) - English

Resource type - Journals

eISSN - 2069-6086

pISSN - 1843-0791

DOI - 10.37897/rjr.2017.2.9

Subject(s) - interstitial lung disease , myositis , antibody , medicine , myopathy , immunology , lung , disease , rheumatoid arthritis , pathology

Anti-synthetase syndrome (SAS) is an autoimmune inflammatory myopathy, whose immune profile is dominated by anti-RNA synthetase antibodies (ARS), with a specific clinical phenotype. The major diagnostic criteria of SAS include the triad of myositis, arthritis and interstitial lung disease (ILD), on the background of positive anti-ARS antibodies. ILD in SAS, has a good evolution compared to the one in PM/DM, due to protective presence of anti Jo-1 antibodies.

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