Open AccessATYPICAL PRESENTATION IN A CASE OF GRANULOMATOSIS WITH POLYANGIITIS
Author(s) -
Cristina Capuşă,
Ana-Maria Mehedinti,
Claudia Toma,
Violeta Bojincă
Publication year - 2016
Publication title -
romanian journal of rheumatology
Language(s) - English
Resource type - Journals
eISSN - 2069-6086
pISSN - 1843-0791
DOI - 10.37897/rjr.2016.1.5
Subject(s) - granulomatosis with polyangiitis , medicine , rapidly progressive glomerulonephritis , glomerulonephritis , proteinase 3 , vasculitis , anti neutrophil cytoplasmic antibody , pathology , respiratory tract , nephritis , microscopic polyangiitis , presentation (obstetrics) , immunology , kidney , respiratory system , disease , surgery
Granulomatosis with polyangiitis (GPA) is part of the anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitis, mostly being ANCA-c (anti proteinase 3) positive. Primarily it involves the upper respiratory tract and kidneys having an increased mortality in the absence of early diagnosis and correct treatment. The most common renal involvement is pauci-immune crescentic glomerulonephritis. We present the case of a patient with GPA with a particular onset of interstitial nephritis, possible by vasa recta vasculitis, in the absence of glomerulonephritis.