Open AccessRetinoids and teratogenicity
Author(s) -
Lucian Pop,
Nicolae Bacalbaşa,
Irina Bălescu,
Vlad Dima,
Roxana Elena Bohîlţea
Publication year - 2021
Publication title -
romanian journal of pediatrics
Language(s) - English
Resource type - Journals
eISSN - 2069-6175
pISSN - 1454-0398
DOI - 10.37897/rjp.2021.4.3
Subject(s) - isotretinoin , retinoid , acne , fertility , pregnancy , medicine , teratology , induced abortions , family planning , fetus , physiology , gynecology , obstetrics , population , dermatology , biology , retinoic acid , research methodology , environmental health , biochemistry , genetics , gene
For more than 30 years, retinoids have been used for acne treatment also their teratogenic effects are widely known. For any woman at a fertility age and under retinoid treatment, a contraception program should be in place. Pregnancy should be postponed until the completion of treatment and one month afterwards. Multiple fetal abnormalities are directly linked to isotretinoin.