Open AccessTHROMBOEMBOLIC DISEASE IN CHILDREN (EPIDEMIOLOGY, ETIOPATHOGENY AND DIAGNOSIS) (I)
Author(s) -
Otilia-Elena Frăsinariu,
Iași Pharmacy,
Violeta Ştreangă,
Aurica Rugină,
Irina Mihaela Ciomaga,
Nicolai Nistor
Publication year - 2016
Publication title -
romanian journal of pediatrics
Language(s) - English
Resource type - Journals
eISSN - 2069-6175
pISSN - 1454-0398
DOI - 10.37897/rjp.2016.2.2
Subject(s) - medicine , fibrinolysis , epidemiology , hemostasis , intensive care medicine , disease , incidence (geometry) , thrombosis , pediatrics , surgery , pathology , physics , optics
Thrombosis is the result of an imbalance between two complex systems: hemostasis and fibrinolysis. Although the incidence of thromboembolism is lower in children than in adults, the associated morbidity is clinically relevant. This paper summarizes the main risk factors – important in defining effective strategies for primary thrombo-prophylaxis in children at risk, the diagnostic criteria and the optimal therapeutic approach, which have mostly been extrapolated from the adult’s recommendations until now.