Open AccessBISPHOSPHONATE THERAPY IN PEDIATRIC PATIENTS WITH OSTEOGENESIS IMPERFECTA
Author(s) -
Alina Murgu,
Roxana Creţu,
Adnana Jaramani,
Elena Macsim,
Ana Maria Chiforeanu
Publication year - 2015
Publication title -
romanian journal of pediatrics
Language(s) - English
Resource type - Journals
eISSN - 2069-6175
pISSN - 1454-0398
DOI - 10.37897/rjp.2015.2.14
Subject(s) - osteogenesis imperfecta , medicine , bisphosphonate , connective tissue , pediatrics , osteoporosis , pathology
Osteogenesis imperfecta (OI) is a group of rare inherited disorders of connective tissue with the common feature of excessive fragility of bones caused by mutations in collagen. We present the case of 2 patients diagnosed with different types of OI, both males, one admitted in the neonatal period and one in infancy. The aim of the study was to compare the efficiency of bisphosphonate therapy, following up the quality of life after receiving it, or in the absence of this treatment.