Open AccessInvestigating dysautonomia of Bradbury Eggleston syndrome: A case report
Author(s) -
Soumayata Somendra,
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Amit Tak,
Jyotsna Shukla,
Kapil Gupta,
Jitendra Gupta,
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Publication year - 2021
Publication title -
romanian journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 4
eISSN - 2069-6094
pISSN - 1843-8148
DOI - 10.37897/rjn.2021.3.20
Subject(s) - dysautonomia , nocturia , medicine , supine position , orthostatic vital signs , autonomic function , heart rate variability , autonomic nervous system , cardiology , heart rate , blood pressure , disease , urinary system
This is a report of 65 years old man with recurrent episodes of dizziness while standing from supine position and history of constipation and nocturia since last 6 months. Patient disclosed no significant past history other than treated pulmonary tuberculosis 5 years back. The general mental state and vital parameters were within normal limits. Autonomic function tests and heart rate variability analysis measured autonomic reactivity and tone respectively. The tests revealed that autonomic dysfunction include severe sympathetic and mild parasympathetic involvement. After exclusion of other possible causes of orthostatic hypertension, diagnosis of pure autonomic failure also known as Bradbury Eggleston syndrome was established. Treatment with fludrocortisones and non-pharmacological interventions improved orthostatic tolerance.