Open AccessCHRONIC NEUROLOGICAL DISEASE AS AN INDEPENDENT RISK FACTOR FOR DEATH IN SEVERE COVID-19 CASES
Author(s) -
Edson Cristóvão Silveira
Publication year - 2021
Publication title -
romanian journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 4
eISSN - 2069-6094
pISSN - 1843-8148
DOI - 10.37897/rjn.2021.2.15
Subject(s) - medicine , context (archaeology) , poisson regression , covid-19 , risk factor , disease , univariate , univariate analysis , multivariate analysis , mortality rate , protective factor , multivariate statistics , infectious disease (medical specialty) , population , paleontology , statistics , mathematics , environmental health , biology
COVID-19 is a multisystemic disease with a wild severity range, being some chronic diseases risk factors for unfavorable evolution. It has been suggested are chronic neurological diseases are associated to higher mortality in COVID-19 patients; such association however, has not been described enough. In this context, this study seeks to evaluate whether the presence of previous chronic neurological disease is a factor associated with higher mortality in hospitalized severe cases of COVID-19. For this, the association between those variables was investigated in 87,871 patients through univariate (risk ratio and χ2 test) and multivariate (Poisson regression) analysis. It was found that the mortality rate for patients presenting chronic neurological disease was 23% higher (),this being an independent and statistically significant association (RR = 1.23, 95% CI = 1.2-1.3; p-value < 0.001). Therefore, more studies are needed to better characterize this association.