Open AccessMULTIPLE CEREBRAL MELANOMA METASTASES WITH UNKNOWN PRIMARY TUMOR LOCATION: A CASE REPORT
Author(s) -
Liviu Cozma,
Delia Tulbă,
Maria Barsevschi,
Cristina Mitu,
Laura Dumitrescu,
Radu Tănăsescu,
Bogdan Ovidiu Popescu,
Bucharest Pharmacy
Publication year - 2017
Publication title -
romanian journal of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.111
H-Index - 4
eISSN - 2069-6094
pISSN - 1843-8148
DOI - 10.37897/rjn.2017.4.9
Subject(s) - medicine , melanoma , radiosurgery , stereotactic biopsy , radiology , biopsy , magnetic resonance imaging , brain biopsy , brain tumor , pathology , radiation therapy , cancer research
. Diagnostic and therapeutic approach of multiple cerebral lesions is often challenging. Case report. A 66-year-old man with unremarkable medical history was admitted to our hospital for recent inability and stereotyped movements of the left upper limb. Brain MRI identified eight tumoral masses with contrast enhancement and marked SWI signal loss that displayed increased metabolic activity on 18F-FDG PET/CT scan. Cerebral biopsy led to the diagnosis of melanoma with BRAF V600E mutation. Stereotactic radiosurgery and molecular therapy were planned afterwards. Conclusion. Brain MRI is an useful tool in guiding diagnosis of cerebral metastases of unknown origin.