Open AccessPeculiarities of topical therapy in pediatric psoriasis
Author(s) -
Ana Maria Alexandra Stănescu,
Vlad Dima,
Ioana Veronica Grăjdeanu,
Mira Florea,
Anca A. Simionescu
Publication year - 2021
Publication title -
romanian journal of medical practice
Language(s) - English
Resource type - Journals
eISSN - 2069-6108
pISSN - 1842-8258
DOI - 10.37897/rjmp.2021.s4.12
Subject(s) - psoriasis , medicine , dermatology , disease , population , pathology , environmental health
In children and adolescents, psoriasis affects between 0.5% and 1.2% of the population. Currently, at least 80 chromosomal loci have been discovered that are significantly linked to psoriasis, and some of these loci are mainly linked to the onset of psoriasis in childhood. Pediatric psoriasis can be more difficult to diagnose due to an easier course of the disease, with smaller and thinner plaques, which are less scalable and with atypical manifestations. First-line therapy in psoriasis in both children and adults is represented by topical therapy. Treatment options for psoriasis in children and adolescents are largely off-label, with little data available on efficacy and safety.