Open AccessHypertensive disorders in twin pregnancy
Author(s) -
Ana Duminica-Turcu,
Nicolae Gică,
Brînduşa Ana Cimpoca-Raptis,
Anca Marina Ciobanu,
Corina Gică,
Radu Botezatu,
Gheorghe Peltecu,
Anca Maria Panaitescu
Publication year - 2021
Publication title -
romanian journal of medical practice
Language(s) - English
Resource type - Journals
eISSN - 2069-6108
pISSN - 1842-8258
DOI - 10.37897/rjmp.2021.s3.7
Subject(s) - medicine , hellp syndrome , preeclampsia , pregnancy , eclampsia , gestational hypertension , obstetrics , fetus , pathophysiology , chronic hypertension , blood pressure , gestation , genetics , biology
Hypertensive disorders such as gestational hypertension, preeclampsia, eclampsia and HELLP syndrome are one of the most common pregnancy-associated entities that imply substantial maternal-fetal mortality and morbidity. When hypertensive disorders are associated with a multiple pregnancy, the outset is established sooner, with a rapid evolution and a more severe development. Although, the pathophysiology of hypertensive disorders is not fully understood, there are several risk factors that could be identified. A multiple pregnancy implies additional risks due to specific features: larger or multiple placentas, failure of the uteroplacental unit to uphold the natural development of multiple fetuses or elevated risk of abnormal placental site. Hypertensive disorders include complications that are common for both single and multiple pregnancies, complications such as kidney failure, liver dysfunction, neurological or hematological malfunction, among others. Maternal features, including mean arterial blood pressure, uterine artery pulsatility index and blood levels of PAPP-A and/or PlGF could be determined at an early age and used as screening methods.