Open AccessClinical applications of endometrial receptivity tests in patients with recurrent implantation failure
Author(s) -
Ioan Boleac,
M. Neagu,
Anca Coricovac,
Dorina Codreanu,
Alina Busan-Pirvoiu,
Bogdan Marinescu,
Bucharest Pharmacy
Publication year - 2021
Publication title -
romanian journal of medical practice
Language(s) - English
Resource type - Journals
eISSN - 2069-6108
pISSN - 1842-8258
DOI - 10.37897/rjmp.2021.1.14
Subject(s) - implantation failure , embryo transfer , medicine , gynecology , retrospective cohort study , endometrium , embryo , pregnancy , obstetrics , surgery , infertility , biology , genetics , microbiology and biotechnology
Recurrent implantation failure is represented by the failure to achieve a clinical pregnancy after transfer of at least 4 good-quality embryos in a minimum of 3 fresh or frozen cycles in a woman under the age of 40 years. One of the recent approaches in studying the window of implantation was building the expression profile of the genes of the endometrial cells. We performed a retrospective study which investigated if endometrial receptivity tests improved the outcomes of IVF procedures in patients with recurrent implantation failure. We enrolled 47 couples with RIF and divided them in 2 groups: the first group of 22 couples performed the ERA test and the embryo transfer according to the result of the test; the second group of 27 couples had the embryo transfer done without the ERA test. Our conclusion was that the ERA test did not improve the outcomes for patients with recurrent implantation failure.