Open AccessUTILITY OF INTRAPERITONEAL HYPERTHERMIC CHEMOTHERAPY IN PERITONEAL CANCER FROM ENDOMETRIAL CANCER – LITERATURE REVIEW
Author(s) -
Nicolae Bacalbaşa,
Irina Bălescu
Publication year - 2017
Publication title -
romanian journal of medical practice
Language(s) - English
Resource type - Journals
eISSN - 2069-6108
pISSN - 1842-8258
DOI - 10.37897/rjmp.2017.4.8
Subject(s) - medicine , hyperthermic intraperitoneal chemotherapy , debulking , ovarian cancer , endometrial cancer , peritoneal carcinomatosis , intraperitoneal chemotherapy , chemotherapy , disease , cancer , colorectal cancer , oncology , stage (stratigraphy) , surgery , surgical oncology , cytoreductive surgery , paleontology , biology
Once the benefits of intraperitoneal heated chemotherapy has been widely reported in patients presenting colorectal, appendicular or even ovarian malignancies, this method has been proposed as a therapeutic strategy in treating peritoneal carcinomatosis with various origins such as gastric cancer, breast cancer or even endometrial cancer. Although most often patients presenting endometrial cancer are diagnosed in an early stage of the disease and are submitted to surgery with curative intent, in certain cases the diagnostic is established only later in the evolution of the disease, when disseminated peritoneal lesions are present. In all these cases an aggressive surgical approach consisting to debulking surgery to no residual disease seems the best therapeutic option in order to achieve a good control of the disease. Moreover, it has been stipulated that association of intraperitoneal heated chemotherapy might improve the long term outcomes of such patients. This is a literature review regarding the utility of intraperitoneal heated chemotherapy in treating peritoneal carcinomatosis with endometrial origin.