Open AccessThe antibiotic therapy in pregnancy
Author(s) -
Constantin Dimitrie Nanu,
Cătălina Diana Stănică,
Adrian Neacşu,
Oneaga Gabriela
Publication year - 2016
Publication title -
romanian journal of medical practice
Language(s) - English
Resource type - Journals
eISSN - 2069-6108
pISSN - 1842-8258
DOI - 10.37897/rjmp.2016.4.7
Subject(s) - medicine , pregnancy , antibiotics , fetus , antiseptic , intensive care medicine , antibiotic therapy , obstetrics , obstetrics and gynaecology , pathology , genetics , microbiology and biotechnology , biology
A number of drugs can cross the placenta, having a teratogenic and embryotoxic effect on the fetus. For more than half of the drugs currently used, we do not have appropriate studies in order to reveal their effects on the mother or fetus. However, 45-95% of pregnant women are taking medications during pregnancy, 7% of them are continuing a treatment for a disease diagnosed before pregnancy. 17% of pregnant women receive antibiotics. Antibiotic prophylaxis has created a dangerous “false security”, to circumvent then the aseptic and antiseptic traditional gestures. In obstetrics, antibiotic therapy should take into account the particular field of the host and the existence of the first development stages of the fetus until the end of pregnancy. Antibiotic therapy has an undeniable and important contribution in modern obstetrics, but their prophylactic administration does not cover technical, aseptic and antiseptic errors, producing also an antibiotic resistance. The use of antibiotic therapy is required in cases with higher risk: long labor, ruptured membranes, obstetrical maneuvers, dragged patients or with underlying conditions.