Open AccessManagement of a case of supra-acute immune thrombocytopenic purpura in pregnancy finalized with splenectomy
Author(s) -
Adriana Eleica,
Ana Maria Vlădăreanu,
Minodora Onisâi,
Ion Dumitru,
Cristina Marinescu,
Felicia MIHAI,
Florin ANCA,
D. Vasile,
Raluca Petre,
Andreea BIRJARU,
Elena Copaciu
Publication year - 2015
Publication title -
romanian journal of medical practice
Language(s) - English
Resource type - Journals
eISSN - 2069-6108
pISSN - 1842-8258
DOI - 10.37897/rjmp.2015.1.12
Subject(s) - splenectomy , medicine , thrombocytopenic purpura , spherocytosis , hereditary spherocytosis , fulminant , hematological disorders , thalassemia , immune system , immunology , spleen
Splenectomy is a therapeutic procedure for a wide range of conditions, mainly hematological disorders. From the hematological disorders we can mention the red cell disorders: haemolytic anemia, hereditary spherocytosis and thalassemia, that have indication for splenectomy in case of failure to the drug treatment. A wide variety of thrombocytopenic disorders are improved by splenectomy, and the most common indicatios is for Idiopatic Thrombocitopenic Purpura (ITP). However, splenectomy imparts a high risk of fulminant infections that can be avoided with proper prophylaxis. Although in ITP splenectomy in not curative, it does not remove the autoimmune component, it will lead to relief of symptoms, improved platelet count with the cessation of the immunosuppressant treatment and better quality of life.