Open AccessImportance of Organophosphorus Compounds in Medicinal Chemistry Field
Author(s) -
Petri A. Turhanen
Publication year - 2022
Publication title -
journal of biomedical research and environmental sciences
Language(s) - English
Resource type - Journals
ISSN - 2766-2276
DOI - 10.37871/jbres1421
Subject(s) - chemistry , adenosine triphosphate , cytosol , mitochondrion , energy metabolism , biochemistry , calcium , phosphorus , metabolism , biophysics , enzyme , biology , organic chemistry , endocrinology
Organophosphorus chemistry has a crucial role in the field of drug research [1]. As generally well known, the Adenosine Triphosphate (ATP) plays a key role in the energy processes in all living cells of mammals. There are also natural phosphorus containing organic compound, Phosphocitrate (PC), found in mammalian mitochondria, likely produced by cytosolic phosphorylation of citrate, and which has important role in calcium metabolism, e.g. inhibiting hydroxyapatite precipitation in cells [2-4].