Open AccessRisk Factors and Outbreak Management of Brucellosis in Asia
Author(s) -
Siti Rasidah Abdul Ghani,
Mohammad Saffree Jeffree,
Mohd Rohaizat Hassan,
Syed Sharizman Syed Abdul Rahim,
Nicholas Tze Ping Pang,
Suhaiza Mohd Fadzil,
Noor Atika Azit
Publication year - 2022
Publication title -
infektološki glasnik
Language(s) - English
Resource type - Journals
eISSN - 1848-7769
pISSN - 1331-2820
DOI - 10.37797/ig.41.2.2
Subject(s) - brucellosis , outbreak , livestock , environmental health , odds ratio , checklist , veterinary medicine , medicine , public health , zoonosis , geography , biology , virology , pathology , paleontology , forestry
Objectives: Brucellosis affecting both humansand animals has been present in Asia for many generations. It continues to be amajor public health concern, particularly where livestock is a major source offood and income. The study aims to analyse the risk factors of brucellosis andcompare the outbreak management among Asian countries. Methods: A systematic search was performed fromPubMed, Scopus and Web of Science search engines using the PRISMA checklist2009. PICO tool was applied for keyword search. A total of 14 articles wereincluded in qualitative synthesis and four articles were included in ameta-analysis. The included studies originated from high endemic countries andlow endemic countries. Results: Most cases had a direct contact withthe infected animal through occupational exposure. The overall odds ratio forconsumption of raw animal products was 9.51 (3.24,27.92), P<0.05. For thehistory of contact with an infected animal, the overall odds ratio was 5.74 (1.89,17.39),P<0.05. The livestock related workers also had a significant overall oddsratio, 4.45 (1.15,17.19), P<0.05. Conclusion: The common risk factors for humanbrucellosis outbreak are consumption of infected animal products, history ofcontact with animals and livestock related workers. As the outbreak of humanbrucellosis and animal brucellosis is interrelated, an integrated approach tooutbreak management is crucial.