
Oral Health-Related Quality of Life in Patients with Dystrophic Epidermolysis Bullosa
Author(s) -
Giulio Fortuna,
Massimo Aria,
Sarah Whitmire,
Rodrigo CepedaValdés,
Sandra Cecilia García-García,
María Guadalupe Moreno Treviño,
Julio C. SalasAlanís
Publication year - 2018
Publication title -
american journal of oral medicine
Language(s) - English
Resource type - Journals
ISSN - 2474-1418
DOI - 10.37786/ajom.38
Subject(s) - medicine , quality of life (healthcare) , depression (economics) , epidermolysis bullosa , anxiety , oral health , mucocutaneous zone , gastroenterology , dermatology , dentistry , psychiatry , disease , nursing , economics , macroeconomics
Background: Dystrophic epidermolysis bullosa (DEB) is a devastating mucocutaneous inherited disorder that can have a remarkable impact on the oral cavity.
Objective: To understand the relationships between oral health-related quality of life and general quality of life in DEB patients versus a control group.
Methods: Twenty-eight DEB patients and 26 healthy individuals completed the following battery of scales: Oral Health Impact Profile (OHIP-49), RAND Short Form-36 (SF-36), Hamilton Rating Scale for anxiety (HAM-A) and depression (HAM-D).
Results: All 7 dimensions in OHIP-49 demonstrated significant difference in functional limitations (Median:13.0; IQR:10.3-20.0 vs Median:7.0; IQR:2.0-9.0; p 0.05).
Conclusions: The oral health-related quality of life is highly impaired in patients with DEB. General quality of life was affected only for some dimensions and was not correlated with oral health-related quality of life.