Open AccessDIAGNOSTIC FEATURES OF PSEUDOCYST WALL FORMATION AND INFLAMMATORY ACTIVITY IN CHRONIC PANCREATITIS
Author(s) -
O.M. Babii,
B.F. Shevchenkо,
A. V. Tuzko,
І.А. Кленіна,
О.П. Петішко
Publication year - 2020
Publication title -
harkìvsʹka hìrurgìčna škola
Language(s) - English
Resource type - Journals
ISSN - 2308-7005
DOI - 10.37699/2308-7005.2.2020.13
Subject(s) - medicine , pancreatitis , inflammation , gastroenterology , acute pancreatitis , biopsy
Summary. Objective. To increase the efficiency of diagnostics in determining the wall formation of the pancreatic pseudocyst and the activity of the inflammatory process.
Materials and methods. A total of 99 patients were examined who underwent digestive tract surgery from 2006 to 2019 with pseudocyst that developed on the background of acute and chronic pancreatitis.
There were 73 males (73.74 %), 26 females (26.26 %), 21 to 74 years of age (47.55–2.4 years). Based on the morphological data of the biopsy material, pancreatic pseudocyst (PC) wall formation and inflammatory activity in chronic pancreatitis, patients were divided into two representative groups: Group I (n = 41) — patients with formed wall of PC, group II (n=58) — patients with unformed PC wall. Morphology data were compared with the data of immunological parameters and radiation diagnostic methods.
Results. The TNF-α/IL-10 ratio was higher (p 7.6 kPa (sensitivity — 80.0 %, specificity 78.9 %).
Conclusions. Indices of TNF-α/IL-10, IL-6/IL-10, PMN-elastase, ultrasound, MSCT, SWE have been determined, which allow to evaluate the formation of PC wall and the activity of the inflammatory process.