Open AccessFEATURES OF THE EARLY PROCESS IN DIABETIC FOOT SYNDROME
Author(s) -
V. P. Polyovyy,
Bilel Khorshani,
V. V. Petrynych,
P. V. Kyfyak,
O. V. Tkachuk,
R. І. Sydorchuk
Publication year - 2020
Publication title -
harkìvsʹka hìrurgìčna škola
Language(s) - English
Resource type - Journals
ISSN - 2308-7005
DOI - 10.37699/2308-7005.2.2020.04
Subject(s) - granulation tissue , pathology , connective tissue , medicine , epithelial tissue , dermis , infiltration (hvac) , wound healing , biopsy , diabetic foot , edema , epithelium , surgery , diabetes mellitus , physics , endocrinology , thermodynamics
Summary. Diabetic foot syndrome (DFS) is one of the most common surgical diseases.
The aim of the study: to determine the features of the wound process in the DFS.
Materials and methods. Multimodal pathomorphological study of biopsy material in 120 cases of surgical treatment of DFS was performed.
Results and discussion. During the development of the wound process in the DFS, histologically determined reduction of edema, cellular infiltration, microcirculatory disorders in the marginal area of the wound in the dynamics of treatment. It is found in granulation tissue and in the dermis adjacent to intact skin, a large number of hairy cells. Microcirculatory disorders are expressed in the form of venular plethora, the phenomena of stasis in the capillaries, hemolysis of erythrocytes and the marginal standing of the formed elements in the venules and capillaries. The DFS is characterized by the appearance of foci of destruction and lysis of the newly formed epithelium, which is not observed in the normal wound process.
Conclusions. The formation of granulation tissue is slow, mainly in the form of unformed connective tissue without the formation of classic granulations.