FEATURES OF THE DYNAMICS OF THE I DEGREE OF SEVERETY BACTERIAL KERATITES IN DIABETIC PATIENTS

Summary. Diabetes mellitus (DM) is a risk factor for severe bacterial keratitis, which often leads to complications. The aim was to identify the features of the dynamics of the I degree of severity bacterial keratitis in diabetic patients. Materials and methods. The results of treatment of 15 patients with type 1 DM and bacterial keratitis of the I degree of severity (main group) and 20 patients with bacterial keratitis of the I degree of severity without DM (control group) were analyzed. The severity of bacterial keratitis was determined according to our proposed scheme with a total score of ≤ 14. All patients were treated with instillations of ofloxacin, antiseptics, antioxidants, reparents, artificial tears, mydriatics, systemic anti-inflammatory therapy. In addition to standard, ophthalmic examination methods included bacteriological examination, fluorescein test, OCT of the anterior segment of the eye, non-contact corneal esthesiometry. Results and discussion. In diabetic patients with bacterial keratitis of the I degree of severity the degree of inflammatory reaction in the anterior chamber of the eye and the average threshold of corneal sensitivity at all airflow temperatures at the first visit exceeded the indicators of controls (p<0.05). The degree of the average corneal sensitivity threshold decrease throughout the observation, the degree of pericorneal injection, the size of the corneal ulcer, the depth of corneal infiltration from the 3rd day of observation, the depth of corneal ulcer and corneal edema from the 7th day exceeded indicators of controls (p<0.05). Conclusions. Diabetic patients have features of the dynamics of the I degree of severity bacterial keratitis, which lead to prolongation of the disease and worsening of its consequences.