Open AccessRESEARCH ON THE EFFICIENCY OF THE USE OF THE SORBENT COMBINATION AND ANTISEPTICS IN THE COMPLEX TREATMENT OF PERITONITIS
Author(s) -
I. I. Bilуk,
B. V. Petriuk,
Oleksandr Rotar,
I. I. Dutka,
I. E. Semeniuk
Publication year - 2020
Publication title -
harkìvsʹka hìrurgìčna škola
Language(s) - English
Resource type - Journals
ISSN - 2308-7005
DOI - 10.37699/2308-7005.1.2020.07
Subject(s) - antiseptic , exudate , sorbent , population , peritonitis , microbiology and biotechnology , incubation , medicine , flora (microbiology) , chemistry , biology , surgery , bacteria , adsorption , pathology , biochemistry , genetics , environmental health , organic chemistry
Summary. The aim of the study was to investigate the effectiveness of using a combination of antiseptic and sorbent for decontamination of the abdominal cavity in patients with diffuse peritonitis. The study of isolated peritoneal exudate obtained in patients with diffuse appendicular peritonitis. The exudate determined the species composition and population level of the micro flora before and during the 24-hour incubation without sorbent and antiseptic and their combined use. Bench studies have shown that peritoneal exudate of patients with acute appendicitis, complicated by peritonitis, is contaminated with microorganisms belonging to different taxonomic groups. The anaerobic-aerobic associations of bacterroids, Escherichia coli and fecal enterococcus were dominant among the detected microorganisms. With in 24 hours of incubation, the population level of exudate micro flora increased, which was incubated without sorbent and antiseptic. In a series of studies where the exudate was incubated with the sorbent, a significant decrease in the population level of the micro flora was observed. The combination of sorbent and antiseptic retained its detoxifying and decontaminating properties with respect to toxic factors and pathogens of peritoneal exudate throughout the incubation period, however, the most pronounced properties were observed during the first 12 hours of incubation. Their combined use has been shown to reduce bacterial contamination of peritoneal exudate and reduce the risk of postoperative complications.