Open AccessDISRUPTION OF CARBOHYDRATE METABOLISM IN PATIENTS WITH SEPSIS
Author(s) -
С. Д. Шаповал,
И. Л. Савон,
О. О. Максимова,
L. A. Vasilevskaja,
M. M. Sofilkanich,
O. V. Tribushnoj
Publication year - 2020
Publication title -
harkìvsʹka hìrurgìčna škola
Language(s) - English
Resource type - Journals
ISSN - 2308-7005
DOI - 10.37699/2308-7005.1.2020.04
Subject(s) - sepsis , medicine , diabetes mellitus , carbohydrate metabolism , gangrene , diabetic foot , surgery , endocrinology
Summary. Introduction Every year, 18–20 million cases of sepsis are recorded in the world, 30 % of which result in death. Hopes that with the development of sanitary-hygienic measures the dynamics of sepsis will decrease, turned out to be illusory. The annual increase in the frequency of sepsis is 8.7 %, while it is noted that the number of patients with impaired carbohydrate metabolism increases by 8-27 %.
Materials and methods. 5612 case histories of patients with purulent-septic diseases who were treated at the center for the period 2015-2019 were analyzed.
Results. It was found that 213 (3.8 %) patients had diabetes mellitus (DM) type I or II (group 1), and the number of patients with complicated diabetic foot syndrome (SDS) was 43.3 % of the total number of patients (2431 patients) — 2 group. The development of sepsis in patients of the 1st group was recorded in 1.4 % of cases (46 patients), while in patients with complicated SDS — in 8.3 % (202 patients). Among the latter, in the overwhelming majority of cases, the starting point in the development of sepsis was “wet” gangrene of the lower extremities.
Conclusions. In patients with diabetes, the risk of developing septic complications is significantly higher than in patients without impaired carbohydrate metabolism.