z-logo
open-access-imgOpen Access
Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity
Author(s) -
Roberto Vázquez-Muñoz,
Belén Borrego,
Karla JuarezMoreno,
Maritza Roxana García-García,
Josué D. MotaMorales,
Nina Bogdanchikova,
Alejandro Huerta-Saquero
Publication year - 2018
Publication title -
revista de ciencias tecnológicas
Language(s) - English
Resource type - Journals
ISSN - 2594-1925
DOI - 10.37636/recit.v11811
Subject(s) - silver nanoparticle , toxicity , biology , nanoparticle , nanotechnology , chemistry , materials science , organic chemistry
Currently, silver nanoparticles (AgNPs) are extensively studied for biomedical applications, but although nanomaterials provide many benefits, recently their comparative toxicity have barely been explored. In the current work, AgNPs toxicity on biological systems of different levels of complexity was assessed in a comprehensive and comparatively way. The organisms included viruses, bacteria, microalgae, fungi, animal and human cells (including cancer cell lines). We found that growth of biological systems of different taxonomical groups –in vitro, at a cellular level- is inhibited at concentrations of AgNPs within the same order of magnitude (101 μg/ml). Thus, the AgNPs toxicity does not depend on the complexity of the organisms. The fact that cells and virus are inhibited with a concentration of AgNPs within the same order of magnitude could be explained considering that silver affects fundamental structures for cells and virus alike.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here