Prevalence of frailty and its correlation with chronic non-infectious diseases among outpatients in Moscow

The aim of this study was to research the prevalence of frailty and prefrailty and their relationship with chronic non-infectious diseases among outpatients in Moscow. Methods. The study included 356 patients ≥65 years (mean age 74.9 ± 6.1), 80.4% (n = 286) were women. For identify frailty, the phenotype model and the deficit accumulation model were used. The chronic non-infectious diseases was detected by an anamnesis and evaluating medical records. Results. Frailty and prefrailty according to the criteria of the phenotypic model were identified in 8.9% and 61.3% cases; according to the criteria of the deficit accumulation model – in 4.2% and 45.8% cases, resp. The average number of chronic non-infectious diseases was significantly higher in patients with frailty both  – by the phenotype model (4.0 ± 1.3 vs 2.8 ± 1.4) and by the deficit accumulation model (5.8 ± 0.9 vs 2.5 ± 1.2). Taking into account the influence of age, the risk of prefrailty according to the phenotypic model increases 2.7 times in the presence of chronic heart failure; according to the deficit accumulation model – 5.6 times in the presence of coronary heart disease, 4.2 times with in the joint diseases, 3.7 times with diabetes and 3 times with cancer. Conclusion. А high prevalence of prefrailty among outpatients in Moscow 65 years and older, as well as a reliable relationship between frailty and prefrailty with the total number and individual chronic non-infectious diseases were revealed. It is important to take measures to prevent the development and progression of frailty among outpatients, having a potentially high prevalence of chronic non-infectious diseases.