Open AccessVascular ageing in elderly patients with metabolic syndrome
Author(s) -
С. В. Недогода,
В. В. Цома,
Е. В. Чумачек,
В. О. Смирнова,
Р. В. Палашкин
Publication year - 2020
Publication title -
rossijskij žurnal geriatričeskoj mediciny
Language(s) - English
Resource type - Journals
eISSN - 2686-8709
pISSN - 2686-8636
DOI - 10.37586/2686-8636-1-2020-74-80
Subject(s) - arterial stiffness , ageing , metabolic syndrome , dyslipidemia , medicine , cardiology , pulse wave velocity , obesity , blood pressure
Vascular aging is associated with increased arterial stiffness, vascular remodeling, and increased pulse wave propagation rate. This process can be accelerated by cumulative exposure to various factors that damage the arterial wall: arterial hypertension, hyperglycemia, dyslipidemia, smoking, etc. At present, there is no convincing evidence of the preferential effect of certain components of metabolic syndrome that have the greatest impact on the acceleration of vascular aging in older patients. In this regard, a non-interactive study was conducted to calculate vascular age and compare it with passport age in patients over 65 years of age with metabolic syndrome (MS) and obesity, assessing the greatest contribution to vascular ageing in a given age group of different MS components. The study showed that at different age periods MS components have different specific weights in the formation of early vascular aging.