Open AccessMorphological Verification Of Malignant Neoplasm Of The Urinary System With Multiple Bone Metastases
Author(s) -
Shakhanova Shakhnoza Shavkatovna,
Nodir Mahammatkulovich Rakhimov
Publication year - 2021
Publication title -
the american journal of medical sciences and pharmaceutical research
Language(s) - English
Resource type - Journals
ISSN - 2689-1026
DOI - 10.37547/tajmspr/volume03issue06-23
Subject(s) - medicine , pelvis , spinal cord compression , appendicular skeleton , sacrum , pathologic fracture , radiation therapy , pathological , radiology , spinal cord , skeleton (computer programming) , pathology , surgery , anatomy , psychiatry
In metastatic renal cell carcinoma (mRCC), bone is the second most common site of metastases, occurring in one third of patients. Most bone metastases are found in the sacrum, pelvis, spine and proximal limbs. In addition, the majority of bone metastases are osteolytic with elements of destruction; mixed metastases also occur. This predisposes patients to skeletal events such as pathological fracture, spinal cord compression, which implies the prescription of radiation therapy or bone surgery.