Open AccessState Of Purine Exchange And Microalbuminuria In Patients With Metabolic Syndrome
Author(s) -
И М Таштемирова
Publication year - 2021
Publication title -
the american journal of medical sciences and pharmaceutical research
Language(s) - English
Resource type - Journals
ISSN - 2689-1026
DOI - 10.37547/tajmspr/volume03issue01-08
Subject(s) - metabolic syndrome , medicine , microalbuminuria , endocrinology , purine , metabolic control analysis , sympathetic nervous system , blood pressure , chemistry , biochemistry , enzyme , diabetes mellitus
The aim of the given work was study interactions of impairments sympa-thetic – adrenal systems functional condition and processes of peroxidal oxida-tion of lipids in woman with metabolic syndrome. 107women at the age of 25-49 were observation. They were randomized into 3 groups: I (control) – 15 healthy persons, II – 43 patients with arterial hypertension, III – 49 women with arterial hypertension in combination with metabolic syndrome. The results of carried investigations showed that activation of sympathetic adrenal system and processes of peroxidal oxidation of lipids took place in metabolic syn-drome. Marked lowering of sympathetic – adrenal system key ferment catechol-amins (MAO monoaminooxidaze) desamidization activity and considerable ac-tivation of peroxidal oxidation of lipid products which have great significance in revealing the mechanism of metabolic syndrome development were observed in metabolic syndrome. This results in the prolonged toxic influence of catechola-mins on myocardium.