Clinical Course Of Non-Specific Aortoartheritis (Disease Takayasu) (Casefrompractice)

This article discusses the issues of early diagnosis of non-specific aortoarteritis are not generally accepted and therefore remain relevant. Takayasu syndrome (non-specific aortoarteritis) is an autoimmune inflammatory disease that affects the aorta and its branches, belongs to the group of systemic vasculitis, is characterized by the development of productive inflammation in the wall of large arteries leading to their obliteration, there is no pulsation due to frequent cases of loss of pulse in the upper extremities. The course of the disease is progressive with periodic exacerbations and deterioration of blood circulation in ischemic organs, as well as an unfavorable prognosis. Modern data on the etiology, pathogenesis, and clinical picture of Takayasu syndrome are presented. An important role in the diagnosis of non-specific aortoarteritis is played by computer and magnetic resonance imaging, as well as ultrasound examination of vessels that can detect typical signs of stenosis or aneurysm of the arteries. Treatment of the disease with the use of drugs aimed at suppressing the activity Of b cells of the immune system, as well as with the use of an IL-6 receptor inhibitor, is discussed. In order to attract the attention of General practitioners to a rare rheumatological problem – Takayasu aortoarteritis – the results of their own observations are presented. The clinical picture of the disease in a child is described.