Open AccessLupus Nephritis In Systemic Lupus Erythematosus
Author(s) -
Nazarova Nigina Otabek Qizi,
Jabbarov Azim Atakhanovich,
Abduhalikova Nigora Fahriddinovna,
Madazimova Dilrux Xayotjonovna
Publication year - 2020
Publication title -
the american journal of medical sciences and pharmaceutical research
Language(s) - English
Resource type - Journals
ISSN - 2689-1026
DOI - 10.37547/tajmspr/volume02issue10-22
Subject(s) - lupus nephritis , pathogenesis , medicine , systemic lupus erythematosus , nephritis , kidney , disease , immunology , lupus erythematosus , pathology , antibody
The pathogenesis, clinic, and treatment of kidney damage in patients with systemic lupus erythematosus (SLE) are considered. It is noted that if at the beginning of the disease signs of kidney damage are present in 25-50% of SLE patients, then later they are detected in almost 60% of adults and 80% of children. Variants of kidney damage in SLE are described. The pathogenesis of SLE is generally considered on the model of lupus nephritis. The morphological classification of lupus nephritis, features of the main nephrological syndromes, and clinical variants (active and inactive) are presented. It is indicated that the treatment strategy depends on the activity of the disease, the clinical and morphological variant of lupus nephritis.