Open AccessAnalysis of sparse data in pharmacokinetic studies
Author(s) -
И. И. Мирошниченко,
А. Н. Симонов,
Ю.И. Кузьмин,
А. И. Платова
Publication year - 2020
Publication title -
farmakokinetika i farmakodinamika
Language(s) - English
Resource type - Journals
eISSN - 2686-8830
pISSN - 2587-7836
DOI - 10.37489/2587-7836-2020-2-28-33
Subject(s) - resampling , pharmacokinetics , computer science , statistical analysis , statistics , mathematics , artificial intelligence , pharmacology , medicine
Performing pharmacokinetic and statistical analysis in the case of sparse data presents significant difficulties. Using the example of the pharmacokinetic (PK) study of resveratrol in mice, the resampling method was allowed us to obtain individual PK-parameters and perform full-fledged statistical tests.