Open AccessCytokine tatus in patients with recurrent herpes infection
Author(s) -
A. S. Akmeeva,
R. B. Zhamborova,
A. Ya. Aloeva,
A. M. Kakhidov,
I. D. Abdulkadyrova,
D. M. Altamirova,
З. А. Камбачокова,
T. Sh. Tagirova,
A. E. Elkham
Publication year - 2021
Publication title -
antibiotiki i himioterapiâ
Language(s) - English
Resource type - Journals
ISSN - 0235-2990
DOI - 10.37489/0235-2990-2021-66-5-6-35-39
Subject(s) - convalescence , medicine , cytokine , pathological , immunology , disease , gastroenterology
The study of the concentration of the main pro-inammatory cytokines (IL-1β, IL-6 and TNF) in the blood serum of 48 patients with recurrent chronic herpesvirus infection was carried out. A signicant increase of cytokine levels with the maximum values during the height of the disease was established. During the period of clinical symptoms’ subsidence, a decrease in their concentration with incomplete normalization is observed during the period of convalescence. Changes in the level of IL-1β, IL-6 and TNF in the blood serum of patients with recurrent herpesvirus infection depended on the period of the disease and the severity of the pathological process.