Open AccessAntimicrobial Properties of Water-Soluble Polysaccharides and Alcoholic Extracts of <i>Laetiporus Sulphureus</i> (Bull.) Murrill Mycelium and Development of Biotechnology for Its Production in Immobilized Culture on Bacterial Cellulose
Author(s) -
Гаврюшина Ирина Александровна,
Громовых Татьяна Ильинична,
Фельдман Наталия Борисовна,
Луценко Сергей Викторович,
Пономаренко Валерий Иванович,
Кисиль Ольга Валерьевна,
Садыкова Вера Сергеевна
Publication year - 2020
Publication title -
antibiotiki i himioterapiâ
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.112
H-Index - 11
ISSN - 0235-2990
DOI - 10.37489/0235-2990-2020-65-1-2-10-14
Subject(s) - mycelium , food science , antimicrobial , polysaccharide , cellulose , chemistry , biology , botany , microbiology and biotechnology , biochemistry
The article discusses the development of a new method of producing Laetiporus sulphureus (Bull.) Murrill basidiomycete mycelium immobilized on a bacterial cellulose matrix. Mycelium contains biologically active compounds with antimicrobial activity against Gram-positive bacteria, including resistant staphylococcus. The aim of the work was to obtain immobilized mycelium by co-cultivation of L.sulphureus with the producer of bacterial cellulose Gluconacetobacter hansenii . The authors found that when co-culturing the basidial L.sulphureus strain with the bacterial cellulose producing G.hansenii strain, productivity increases by 3.2 times on H5/1 synthetic medium and by 1.9 times on natural Maltax-10 medium (concentration 5%). The resulting immobilized L.sulphureus mycelium has antibacterial properties; its aqueous extracts contain glucans.