Open AccessInvolvement of ATM/ATR-p38 MAPK cascade in MNNG induced G1-S arrest
Author(s) -
Keqing Zhu
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i9.2073
Subject(s) - comet assay , dna damage , microbiology and biotechnology , mapk/erk pathway , p38 mitogen activated protein kinases , kinase , western blot , immunoprecipitation , chemistry , biology , antibody , biochemistry , dna , immunology , gene
To understand the effect of low concentration of N-methyl-N'-nitro-nitrosoguanidine (MNNG), which is a widely distributed environmental mutagen and carcinogen especially for human gastric cancer, on DNA damage and to study its possible pathway in regulating cell cycle arrest.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom