Open AccessGeneration and characterization of transgenic mice expressing tamoxifen-inducible cre-fusion protein specifically in mouse liver
Author(s) -
Hengrui Zhu,
Jianquan Chen,
Guoxiang Cheng,
Jinglun Xue
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i8.1844
Subject(s) - cre recombinase , biology , transgene , genetically modified mouse , microbiology and biotechnology , fusion gene , offspring , gene expression , gene , genetics , pregnancy
To establish transgenic mice expressing tamoxifen-inducible Cre-ERt recombinase specifically in the liver and to provide an efficient animal model for studying gene function in the liver and creating various mouse models mimicking human diseases.