Open AccessExpression of metallothionein gene at different time in testicular interstitial cells and liver of rats treated with cadmium
Author(s) -
Xu-Yi Ren,
Yong Zhou,
Jianpeng Zhang,
Feng Wang,
Binghua Jiao
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i7.1554
Subject(s) - metallothionein , toxicity , messenger rna , biology , gene expression , interstitial cell , gene isoform , testicle , medicine , cadmium , microbiology and biotechnology , endocrinology , basal (medicine) , real time polymerase chain reaction , andrology , chemistry , gene , biochemistry , organic chemistry , insulin
Rodent testes are generally more susceptible to cadmium (Cd)-induced toxicity than liver. To clarify the molecular mechanism of Cd-induced toxicity in testes, we compared metallothionein (MT) gene expression, MT protein accumulation, and Cd retention at different time in freshly isolated testicular interstitial cells and liver of rats treated with Cd.