Open AccessInhibition of HBV targeted ribonuclease enhanced by introduction of linker
Author(s) -
Weidong Gong,
Jun Li,
Jin Ding,
Ya Zhao,
Yinghui Li,
Cong Xue
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i7.1504
Subject(s) - linker , microbiology and biotechnology , plasmid , mtt assay , chemistry , biology , in vitro , biochemistry , dna , computer science , operating system
To construct human eosinophil-derived neurotoxin(hEDN) and HBV core protein (HBVc) eukaryotic fusion expression vector with a linker (Gly(4)Ser) (3) between them to optimize the molecule folding, which will be used to inhibit HBV replication in vitro.