Open AccessEstablishment of transgenic mice carrying the gene of human nuclear receptor NR5A2 (hB1F)
Author(s) -
Shuiliang Wang,
Hua Yang,
Youhua Xie,
Yuan Wang,
Jianzhong Li,
Long Wang,
Zhugang Wang,
Jian Fu
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i6.1333
Subject(s) - transgene , biology , genetically modified mouse , microbiology and biotechnology , southern blot , enhancer , blot , gene , gene expression , genetics
Human hepatitis B virus enhancer II B1 binding factor (hB1F) was cloned and characterized as a novel member of the Ftz-F1 (NR5A) nuclear receptor subfamily. Although progresses have recently been made, its biological function remains largely unidentified. The aim of this study was to establish an hB1F transgenic mouse model to promote the functional study of hB1F.