Open Access
Loss of fragile histidine triad protein in human hepatocellular carcinoma
Author(s) -
Po Zhao
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i6.1216
Subject(s) - fhit , hepatocellular carcinoma , immunohistochemistry , carcinogenesis , pathology , biology , cancer research , carcinoma , tumor suppressor gene , medicine , cancer , genetics
To investigate the expression of fragile histidine triad (FHIT) gene protein, Fhit, which is recently thought to be a candidate tumor suppressor. Abnormal expression of fragile histidine triad has been found in a variety of human cancers, but little is known about its expression in human hepatocellular carcinogenesis and evolution.