Open AccessAnalysis of spontaneous, gamma ray- and ethylnitrosourea-induced hprt mutants in HL-60 cells with multiplex PCR
Author(s) -
Shengxue Liu,
Jia Cao,
Hailong An,
Hua-Min Shun,
Lüjun Yang,
Yong Liu
Publication year - 2003
Publication title -
world journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.427
H-Index - 155
eISSN - 2219-2840
pISSN - 1007-9327
DOI - 10.3748/wjg.v9.i3.578
Subject(s) - microbiology and biotechnology , hypoxanthine guanine phosphoribosyltransferase , exon , mutant , biology , multiplex polymerase chain reaction , gene , mutation , gene mutation , multiplex , ethylnitrosourea , mutation frequency , polymerase chain reaction , genetics
To explore the molecular spectra and mechanism of human hypoxanthine guanine phosphoribosyl transferase (hprt) gene mutation induced by ethyluitrosourea (ENU) and (60)Co gamma-rays.