The microcell mediated transfer of human chromosome 8 into highly metastatic rat liver cancer cell line C5F | Zendy

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The microcell mediated transfer of human chromosome 8 into highly metastatic rat liver cancer cell line C5F

Author(s) -

Hu Liu

Publication year - 2003

Publication title -

world journal of gastroenterology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.427

H-Index - 155

eISSN - 2219-2840

pISSN - 1007-9327

DOI - 10.3748/wjg.v9.i3.449

Subject(s) - biology , chromosome , microbiology and biotechnology , cancer , metastasis , clone (java method) , cloning (programming) , genetics , cancer research , gene , computer science , programming language

Our previous research on the surgical samples of primary liver cancer with CGH showed that the loss of human chromosome 8p had correlation with the metastatic phenotype of liver cancer. In order to seek the functional evidence that there could be a metastatsis suppressor gene(s) for liver cancer on human chromosome 8, we tried to transfer normal human chromosome 8 into rat liver cancer cell line C5F, which had high metastatic potential to lung.

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